Does genetic diversity predict health in humans?
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ABSTRACT:
SUBMITTER: Lie HC
PROVIDER: S-EPMC2712076 | biostudies-literature | 2009 Jul
REPOSITORIES: biostudies-literature
Publications
Does genetic diversity predict health in humans?
Lie Hanne C HC Simmons Leigh W LW Rhodes Gillian G
PloS one 20090727 7
Genetic diversity, especially at genes important for immune functioning within the Major Histocompatibility Complex (MHC), has been associated with fitness-related traits, including disease resistance, in many species. Recently, genetic diversity has been associated with mate preferences in humans. Here we asked whether these preferences are adaptive in terms of obtaining healthier mates. We investigated whether genetic diversity (heterozygosity and standardized mean d(2)) at MHC and nonMHC micr ...[more]
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