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Importance of the Debye screening length on nanowire field effect transistor sensors.

ABSTRACT: Nanowire field effect transistors (NW-FETs) can serve as ultrasensitive detectors for label-free reagents. The NW-FET sensing mechanism assumes a controlled modification in the local channel electric field created by the binding of charged molecules to the nanowire surface. Careful control of the solution Debye length is critical for unambiguous selective detection of macromolecules. Here we show the appropriate conditions under which the selective binding of macromolecules is accurately sensed with NW-FET sensors.

SUBMITTER: Stern E

PROVIDER: S-EPMC2713684 | biostudies-literature | 2007 Nov

REPOSITORIES: biostudies-literature

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Importance of the Debye screening length on nanowire field effect transistor sensors.

Stern Eric E Wagner Robin R Sigworth Fred J FJ Breaker Ronald R Fahmy Tarek M TM Reed Mark A MA

Nano letters 20071003 11

Nanowire field effect transistors (NW-FETs) can serve as ultrasensitive detectors for label-free reagents. The NW-FET sensing mechanism assumes a controlled modification in the local channel electric field created by the binding of charged molecules to the nanowire surface. Careful control of the solution Debye length is critical for unambiguous selective detection of macromolecules. Here we show the appropriate conditions under which the selective binding of macromolecules is accurately sensed ...[more]

PMID: 17914853

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