Ontology highlight
ABSTRACT:
SUBMITTER: Tse KP
PROVIDER: S-EPMC2725267 | biostudies-literature | 2009 Aug
REPOSITORIES: biostudies-literature
Tse Ka-Po KP Su Wen-Hui WH Chang Kai-Ping KP Tsang Ngan-Ming NM Yu Chia-Jung CJ Tang Petrus P See Lee-Chu LC Hsueh Chuen C Yang Min-Lee ML Hao Sheng-Po SP Li Hong-Yi HY Wang Ming-Hsi MH Liao Li-Ping LP Chen Lih-Chyang LC Lin Sheue-Rong SR Jorgensen Timothy J TJ Chang Yu-Sun YS Shugart Yin Yao YY
American journal of human genetics 20090806 2
Nasopharyngeal carcinoma (NPC) is a multifactorial malignancy closely associated with genetic factors and Epstein-Barr virus infection. To identify the common genetic variants linked to NPC susceptibility, we conducted a genome-wide association study (GWAS) in 277 NPC patients and 285 healthy controls within the Taiwanese population, analyzing 480,365 single-nucleotide polymorphisms (SNPs). Twelve statistically significant SNPs were identified and mapped to chromosome 6p21.3. Associations were r ...[more]