Ontology highlight
ABSTRACT:
SUBMITTER: Tang M
PROVIDER: S-EPMC2729998 | biostudies-literature | 2009 Aug
REPOSITORIES: biostudies-literature
Tang Mingqing M Xu William W Wang Qizhao Q Xiao Weidong W Xu Ruian R
Current genomics 20090801 5
Lung cancer, the leading cause of mortality in both men and women in the United States, is largely diagnosed at its advanced stages that there are no effective therapeutic alternatives. Although tobacco smoking is the well established cause of lung cancer, the underlying mechanism for lung tumorigenesis remains poorly understood. An important event in tumor development appears to be the epigenetic alterations, especially the change of DNA methylation patterns, which induce the most tumor suppres ...[more]