Ontology highlight
ABSTRACT:
SUBMITTER: Wang H
PROVIDER: S-EPMC2731986 | biostudies-literature | 2009 Sep
REPOSITORIES: biostudies-literature
Wang Haikun H Liu Jin J Cho Kwang-Hyun KH Ren Dejian D
Biology of reproduction 20090610 3
All four CATSPER channel pore-forming subunits (CATSPER1-4) are localized in the sperm principal piece. They form an alkalization-activated Ca2+-permeable channel and are required for sperm-hyperactivated motility, egg coat penetration, and male fertility. Unlike many other ion channels, the composition of the CATSPER protein complex is poorly defined. Herein, we describe the novel protein CATSPERG associated with the CATSPER complex. CATSPERG is predicted to be a single transmembrane-spanning p ...[more]