Ontology highlight
ABSTRACT:
SUBMITTER: Matthew S
PROVIDER: S-EPMC2748991 | biostudies-literature | 2009 Apr
REPOSITORIES: biostudies-literature
Planta medica 20090212 5
Three unusual tiglic acid-containing cyclodepsipeptides, possessing the revised regioisomeric structures for largamides A-C (1-3), have been isolated from the marine cyanobacterium Lyngbya confervoides collected from southeastern Florida. The two-dimensional structures were determined by NMR spectroscopy and the absolute configurations by chiral HPLC analysis of degradation products. Compounds 1-3 are moderate inhibitors of mammalian elastase activity in vitro with IC(50) values ranging from 0.5 ...[more]