Ontology highlight
ABSTRACT:
SUBMITTER: Mulkidjanian AY
PROVIDER: S-EPMC2752816 | biostudies-literature | 2009 Apr
REPOSITORIES: biostudies-literature
Mulkidjanian Armen Y AY Galperin Michael Y MY Koonin Eugene V EV
Trends in biochemical sciences 20090318 4
Studies of the past several decades have provided major insights into the structural organization of biological membranes and mechanisms of many membrane molecular machines. However, the origin(s) of the membrane(s) and membrane proteins remains enigmatic. We discuss different concepts of the origin and early evolution of membranes with a focus on the evolution of the (im)permeability to charged molecules such as proteins, nucleic acids and small ions. Reconstruction of the evolution of F-type a ...[more]