Ontology highlight
ABSTRACT:
SUBMITTER: Su L
PROVIDER: S-EPMC275392 | biostudies-literature | 1997 Sep
REPOSITORIES: biostudies-literature
Su L L Radek J T JT Labeots L A LA Hallenga K K Hermanto P P Chen H H Nakagawa S S Zhao M M Kates S S Weiss M A MA
Genes & development 19970901 17
Antitermination protein N regulates the transcriptional program of phage lambda through recognition of RNA enhancer elements. Binding of an arginine-rich peptide to one face of an RNA hairpin organizes the other, which in turn binds to the host antitermination complex. The induced RNA structure mimics a GNRA hairpin, an organizational element of rRNA and ribozymes. The two faces of the RNA, bridged by a sheared GA base pair, exhibit a specific pattern of base stacking and base flipping. This pat ...[more]