Ontology highlight
ABSTRACT:
SUBMITTER: Wang J
PROVIDER: S-EPMC2760655 | biostudies-literature | 2009 Oct
REPOSITORIES: biostudies-literature
Journal of molecular biology 20090808 3
We report a "top-down" method that uses mainly duplexes' global orientations and overall molecular dimension and shape restraints, which were extracted from experimental NMR and small-angle X-ray scattering data, respectively, to determine global architectures of RNA molecules consisting of mostly A-form-like duplexes. The method is implemented in the G2G (from global measurement to global structure) toolkit of programs. We demonstrate the efficiency and accuracy of the method by determining the ...[more]