Ontology highlight
ABSTRACT:
SUBMITTER: Wong WW
PROVIDER: S-EPMC2762163 | biostudies-literature | 2009 Nov
REPOSITORIES: biostudies-literature
Wong William W WW Lewis Richard D RD Steinberg Francene M FM Murray Michael J MJ Cramer Margaret A MA Amato Paula P Young Ronald L RL Barnes Stephen S Ellis Kenneth J KJ Shypailo Roman J RJ Fraley J Kennard JK Konzelmann Karen L KL Fischer Joan G JG Smith E O'Brian EO
The American journal of clinical nutrition 20090916 5
<h4>Background</h4>Isoflavones are naturally occurring plant estrogens that are abundant in soy. Although purported to protect against bone loss, the efficacy of soy isoflavone supplementation in the prevention of osteoporosis in postmenopausal women remains controversial.<h4>Objective</h4>Our aim was to test the effect of soy isoflavone supplementation on bone health.<h4>Design</h4>A multicenter, randomized, double-blind, placebo-controlled 24-mo trial was conducted to assess the effects of dai ...[more]