The pediatric burden of human coronaviruses evaluated for twenty years.
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ABSTRACT:
SUBMITTER: Talbot HK
PROVIDER: S-EPMC2765860 | biostudies-literature | 2009 Aug
REPOSITORIES: biostudies-literature
Publications
The pediatric burden of human coronaviruses evaluated for twenty years.
Talbot H Keipp HK Shepherd Bryan E BE Crowe James E JE Griffin Marie R MR Edwards Kathryn M KM Podsiad Amy B AB Tollefson Sharon J SJ Wright Peter F PF Williams John V JV
The Pediatric infectious disease journal 20090801 8
<h4>Background</h4>The epidemiology of human coronaviruses (HCoVs) has not been established using reverse transcription polymerase chain reaction techniques in a specimen collection that spans decades.<h4>Methods</h4>We used real-time RT-PCR for 3 HCoVs, HCoV 229E, OC43, and NL63, to test nasal wash specimens that had been obtained from a cohort of children <5 years of age with upper or lower respiratory infection (URI, LRI) who were comprehensively followed during the period from 1977 to 2001. ...[more]
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