Ontology highlight
ABSTRACT:
SUBMITTER: Salsi V
PROVIDER: S-EPMC2772751 | biostudies-literature | 2009 Nov
REPOSITORIES: biostudies-literature
Salsi Valentina V Ferrari Silvia S Ferraresi Roberta R Cossarizza Andrea A Grande Alexis A Zappavigna Vincenzo V
Molecular and cellular biology 20090824 21
HOX DNA-binding proteins control patterning during development by regulating processes such as cell aggregation and proliferation. Recently, a possible involvement of HOX proteins in replication origin activity was suggested by results showing that a number of HOX proteins interact with the DNA replication licensing regulator geminin and bind a characterized human origin of replication. The functional significance of these observations, however, remained unclear. We show that HOXD13, HOXD11, and ...[more]