Ontology highlight
ABSTRACT:
SUBMITTER: Batista-Brito R
PROVIDER: S-EPMC2773208 | biostudies-literature | 2009 Aug
REPOSITORIES: biostudies-literature
Neuron 20090801 4
We describe the role of Sox6 in cortical interneuron development, from a cellular to a behavioral level. We identify Sox6 as a protein expressed continuously within MGE-derived cortical interneurons from postmitotic progenitor stages into adulthood. Both its expression pattern and null phenotype suggests that Sox6 gene function is closely linked to that of Lhx6. In both Lhx6 and Sox6 null animals, the expression of PV and SST and the position of both basket and Martinotti neurons are abnormal. W ...[more]