Ontology highlight
ABSTRACT:
SUBMITTER: Lankalapalli RS
PROVIDER: S-EPMC2782442 | biostudies-literature | 2009 Nov
REPOSITORIES: biostudies-literature
The Journal of organic chemistry 20091101 22
Sphingolipid phosphate analogues bearing 7-(diethylamino)coumarin (DECM) and 4-bromo-5-hydroxy-2-nitrobenzhydryl (BHNB) groups in a photolabile ester bond were synthesized. The ability of the "caged" ceramide 1-phosphate analogues to release the bioactive parent molecule upon irradiation at 400-500 nm was demonstrated by stimulation of macrophage cell proliferation. ...[more]