Ontology highlight
ABSTRACT:
SUBMITTER: Maki BE
PROVIDER: S-EPMC2782717 | biostudies-literature | 2009 Apr
REPOSITORIES: biostudies-literature
Maki Brooks E BE Scheidt Karl A KA
Organic letters 20090401 7
Indoles and alcohols can be coupled in a dehydrogenative process catalyzed by tetrapropylammonium perruthenate. This efficient approach to indolylamides proceeds in a single flask under mild conditions. By employing substituted indoles and alkyl, branched, or benzylic alcohols, a variety of indolylamides can be formed. Aryl indolylamides can be functionalized through an additional dehydrogenative coupling to furnish elaborated polycyclic heterocycles similar to biologically active structures pre ...[more]