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Green fluorescent proteins are light-induced electron donors.

ABSTRACT: Proteins of the green fluorescent protein (GFP) family are well known owing to their unique biochemistry and extensive use as in vivo markers. We discovered that GFPs of diverse origins can act as light-induced electron donors in photochemical reactions with various electron acceptors, including biologically relevant ones. Moreover, via green-to-red GFP photoconversion, this process can be observed in living cells without additional treatment.

SUBMITTER: Bogdanov AM

PROVIDER: S-EPMC2784199 | biostudies-literature | 2009 Jul

REPOSITORIES: biostudies-literature

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Green fluorescent proteins are light-induced electron donors.

Bogdanov Alexey M AM Mishin Alexander S AS Yampolsky Ilia V IV Belousov Vsevolod V VV Chudakov Dmitriy M DM Subach Fedor V FV Verkhusha Vladislav V VV Lukyanov Sergey S Lukyanov Konstantin A KA

Nature chemical biology 20090701 7

Proteins of the green fluorescent protein (GFP) family are well known owing to their unique biochemistry and extensive use as in vivo markers. We discovered that GFPs of diverse origins can act as light-induced electron donors in photochemical reactions with various electron acceptors, including biologically relevant ones. Moreover, via green-to-red GFP photoconversion, this process can be observed in living cells without additional treatment. ...[more]

PMID: 19396176

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