Ontology highlight
ABSTRACT:
SUBMITTER: Fellay J
PROVIDER: S-EPMC2791220 | biostudies-literature | 2009 Dec
REPOSITORIES: biostudies-literature
PLoS genetics 20091224 12
To extend the understanding of host genetic determinants of HIV-1 control, we performed a genome-wide association study in a cohort of 2,554 infected Caucasian subjects. The study was powered to detect common genetic variants explaining down to 1.3% of the variability in viral load at set point. We provide overwhelming confirmation of three associations previously reported in a genome-wide study and show further independent effects of both common and rare variants in the Major Histocompatibility ...[more]