Ontology highlight
ABSTRACT:
SUBMITTER: Vallejos M
PROVIDER: S-EPMC2811009 | biostudies-literature | 2010 Jan
REPOSITORIES: biostudies-literature
Vallejos Maricarmen M Ramdohr Pablo P Valiente-Echeverría Fernando F Tapia Karla K Rodriguez Felipe E FE Lowy Fernando F Huidobro-Toro J Pablo JP Dangerfield John A JA López-Lastra Marcelo M
Nucleic acids research 20091104 2
In this study, we demonstrate the identification of an internal ribosome entry site (IRES) within the 5'-untranslated region (5'-UTR) of the mouse mammary tumor virus (MMTV). The 5'-UTR of the full-length mRNA derived from the infectious, complete MMTV genome was cloned into a dual luciferase reporter construct containing an upstream Renilla luciferase gene (RLuc) and a downstream firefly luciferase gene (FLuc). In rabbit reticulocyte lysate, the MMTV 5'-UTR was capable of driving translation of ...[more]