Ontology highlight
ABSTRACT:
SUBMITTER: Kraft JJ
PROVIDER: S-EPMC6471432 | biostudies-literature | 2019 Feb
REPOSITORIES: biostudies-literature
Kraft Jelena J JJ Peterson Mariko S MS Cho Sung Ki SK Wang Zhaohui Z Hui Alice A Rakotondrafara Aurélie M AM Treder Krzysztof K Miller Cathy L CL Miller W Allen WA
Pathogens (Basel, Switzerland) 20190228 1
Many plant viral RNA genomes lack a 5' cap, and instead are translated via a cap-independent translation element (CITE) in the 3' untranslated region (UTR). The panicum mosaic virus-like CITE (PTE), found in many plant viral RNAs, binds and requires the cap-binding translation initiation factor eIF4E to facilitate translation. eIF4E is structurally conserved between plants and animals, so we tested cap-independent translation efficiency of PTEs of nine plant viruses in plant and mammalian system ...[more]