Ontology highlight
ABSTRACT:
SUBMITTER: Reitz C
PROVIDER: S-EPMC2819087 | biostudies-literature | 2009 Oct
REPOSITORIES: biostudies-literature
Reitz Christiane C Mayeux Richard R
Annals of the New York Academy of Sciences 20091001
Late-onset Alzheimer's disease (LOAD) is the most common cause of late-onset dementia in western societies. Despite remarkable achievements in human genetics throughout the years, in particular technological advances in gene mapping and in statistical methods that relate genetic variants to disease, to date only a small proportion of the genetic contribution to LOAD can be explained leaving several remaining genetic risk factors to be identified. A possible explanation for the difficulty in gene ...[more]