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Detection of KPC in Acinetobacter spp. in Puerto Rico.

ABSTRACT: During an island-wide PCR-based surveillance study of beta-lactam resistance in multidrug-resistant (MDR) Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa, and Acinetobacter calcoaceticus-baumannii complex isolates obtained from 17 different hospitals, 10 KPC-positive Acinetobacter isolates were identified. DNA sequencing of the bla(KPC) gene identified KPC-2, -3, and -4 and a novel variant, KPC-10. This is the first report of a KPC-type beta-lactamase identified in Acinetobacter species.

SUBMITTER: Robledo IE

PROVIDER: S-EPMC2825984 | biostudies-literature | 2010 Mar

REPOSITORIES: biostudies-literature

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Detection of KPC in Acinetobacter spp. in Puerto Rico.

Robledo Iraida E IE Aquino Edna E EE Santé María I MI Santana Jorge L JL Otero Diana M DM León Carlos F CF Vázquez Guillermo J GJ

Antimicrobial agents and chemotherapy 20091228 3

During an island-wide PCR-based surveillance study of beta-lactam resistance in multidrug-resistant (MDR) Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa, and Acinetobacter calcoaceticus-baumannii complex isolates obtained from 17 different hospitals, 10 KPC-positive Acinetobacter isolates were identified. DNA sequencing of the bla(KPC) gene identified KPC-2, -3, and -4 and a novel variant, KPC-10. This is the first report of a KPC-type beta-lactamase identified in Acinetobacter ...[more]

PMID: 20038618

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