Ontology highlight
ABSTRACT:
SUBMITTER: Xie H
PROVIDER: S-EPMC2829274 | biostudies-literature | 2008 Feb
REPOSITORIES: biostudies-literature
Xie Huirong H Tranguch Susanne S Jia Xiangxu X Zhang Hao H Das Sanjoy K SK Dey Sudhansu K SK Kuo Calvin J CJ Wang Haibin H
Development (Cambridge, England) 20080116 4
The activation of the blastocyst, a process by which it gains competency to attach with the receptive uterus, is a prerequisite for successful implantation. However, the molecular basis of blastocyst activation remains largely unexplored. Combining molecular, pharmacological and physiological approaches, we show here that silencing of Wnt-beta-catenin signaling in mice does not adversely affect the development of preimplantation embryos to blastocysts and uterine preparation for receptivity, but ...[more]