ABC transporters: the power to change.
Ontology highlight
ABSTRACT:
SUBMITTER: Rees DC
PROVIDER: S-EPMC2830722 | biostudies-literature | 2009 Mar
REPOSITORIES: biostudies-literature
Publications
ABC transporters: the power to change.
Rees Douglas C DC Johnson Eric E Lewinson Oded O
Nature reviews. Molecular cell biology 20090301 3
ATP-binding cassette (ABC) transporters constitute a ubiquitous superfamily of integral membrane proteins that are responsible for the ATP-powered translocation of many substrates across membranes. The highly conserved ABC domains of ABC transporters provide the nucleotide-dependent engine that drives transport. By contrast, the transmembrane domains that create the translocation pathway are more variable. Recent structural advances with prokaryotic ABC transporters have provided a qualitative m ...[more]
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