Ontology highlight
ABSTRACT:
SUBMITTER: Thalhammer A
PROVIDER: S-EPMC2846389 | biostudies-literature | 2009 Apr
REPOSITORIES: biostudies-literature
Thalhammer Agnes A Trinidad Jonathan C JC Burlingame Alma L AL Schoepfer Ralf R
Journal of neurochemistry 20090202 2
Densin-180 is a core component of post-synaptic densities, the highly complex molecular assemblies that mediate signaling between neuronal cells. It is a multi-domain scaffold protein characterized by multiple leucine-rich repeat domains plus a single Psd95/Discs large/Zona occludens-1 domain. In its original topology model a single transmembrane segment was proposed with an extracellular N-terminus and an intracellular C-terminus. However, recently discovered in vivo phosphorylation sites are i ...[more]