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PhenomiR: a knowledgebase for microRNA expression in diseases and biological processes.


ABSTRACT: In recent years, microRNAs have been shown to play important roles in physiological as well as malignant processes. The PhenomiR database http://mips.helmholtz-muenchen.de/phenomir provides data from 542 studies that investigate deregulation of microRNA expression in diseases and biological processes as a systematic, manually curated resource. Using the PhenomiR dataset, we could demonstrate that, depending on disease type, independent information from cell culture studies contrasts with conclusions drawn from patient studies.

SUBMITTER: Ruepp A 

PROVIDER: S-EPMC2847718 | biostudies-literature | 2010 Jan

REPOSITORIES: biostudies-literature

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PhenomiR: a knowledgebase for microRNA expression in diseases and biological processes.

Ruepp Andreas A   Kowarsch Andreas A   Schmidl Daniel D   Buggenthin Felix F   Brauner Barbara B   Dunger Irmtraud I   Fobo Gisela G   Frishman Goar G   Montrone Corinna C   Theis Fabian J FJ  

Genome biology 20100120 1


In recent years, microRNAs have been shown to play important roles in physiological as well as malignant processes. The PhenomiR database http://mips.helmholtz-muenchen.de/phenomir provides data from 542 studies that investigate deregulation of microRNA expression in diseases and biological processes as a systematic, manually curated resource. Using the PhenomiR dataset, we could demonstrate that, depending on disease type, independent information from cell culture studies contrasts with conclus  ...[more]

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