Ontology highlight
ABSTRACT:
SUBMITTER: Crich D
PROVIDER: S-EPMC2852025 | biostudies-literature | 2009 Dec
REPOSITORIES: biostudies-literature
The Journal of organic chemistry 20091201 24
Alpha-mannopyranosyl phosphosugars are obtained in 61-90% yields from 4,6-O-benzylidene-protected mannosyl thioglycosides bearing ester functionality in the 3-O-position by coupling reactions with ammonium salts of phosphosugars on activation with 1-benzenesulfinyl piperidine, 2,4,6-tri-tert-butylpyrimidine, and trifluoromethanesulfonic anhydride. Due to the presence of the disarming ester group, only the formation of the alpha-isomer was observed. ...[more]