Ontology highlight
ABSTRACT:
SUBMITTER: Shriver LP
PROVIDER: S-EPMC2858070 | biostudies-literature | 2009 Jun
REPOSITORIES: biostudies-literature
Journal of neuroimmunology 20090425 1-2
Targeted treatment of inflammatory diseases of the central nervous system (CNS) remains problematic due to the complex pathogenesis of these disorders and difficulty in drug delivery. The plant virus, cowpea mosaic virus (CPMV), has recently been explored as a nanoparticle delivery system for therapeutics targeting a number of diseases including cancer and neurodegeneration. To understand the biodistribution of CPMV in the CNS, we examined CPMV uptake during infection of mice with neurotropic mo ...[more]