Ontology highlight
ABSTRACT:
SUBMITTER: Yasuno K
PROVIDER: S-EPMC2861730 | biostudies-literature | 2010 May
REPOSITORIES: biostudies-literature
Nature genetics 20100404 5
Saccular intracranial aneurysms are balloon-like dilations of the intracranial arterial wall; their hemorrhage commonly results in severe neurologic impairment and death. We report a second genome-wide association study with discovery and replication cohorts from Europe and Japan comprising 5,891 cases and 14,181 controls with approximately 832,000 genotyped and imputed SNPs across discovery cohorts. We identified three new loci showing strong evidence for association with intracranial aneurysms ...[more]