Ontology highlight
ABSTRACT:
SUBMITTER: Li C
PROVIDER: S-EPMC4479022 | biostudies-literature | 2015
REPOSITORIES: biostudies-literature
Nature communications 20150513
Gout is one of the most common types of inflammatory arthritis, caused by the deposition of monosodium urate crystals in and around the joints. Previous genome-wide association studies (GWASs) have identified many genetic loci associated with raised serum urate concentrations. However, hyperuricemia alone is not sufficient for the development of gout arthritis. Here we conduct a multistage GWAS in Han Chinese using 4,275 male gout patients and 6,272 normal male controls (1,255 cases and 1,848 co ...[more]