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Multi-gram scale synthesis of FR180204.


ABSTRACT: A concise synthesis of the ERK inhibitor FR180204 has been developed. The synthesis consists of six operationally simple steps and can be utilized to make multi-gram quantities of FR180204.

SUBMITTER: Patnaik S 

PROVIDER: S-EPMC2862695 | biostudies-literature | 2009 Nov

REPOSITORIES: biostudies-literature

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Multi-gram scale synthesis of FR180204.

Patnaik Samarjit S   Dietz Harry C HC   Zheng Wei W   Austin Christopher C   Marugan Juan J JJ  

The Journal of organic chemistry 20091101 22


A concise synthesis of the ERK inhibitor FR180204 has been developed. The synthesis consists of six operationally simple steps and can be utilized to make multi-gram quantities of FR180204. ...[more]

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