Ontology highlight
ABSTRACT:
SUBMITTER: Doherty JA
PROVIDER: S-EPMC2863004 | biostudies-literature | 2010 Jan
REPOSITORIES: biostudies-literature
Doherty Jennifer A JA Rossing Mary Anne MA Cushing-Haugen Kara L KL Chen Chu C Van Den Berg David J DJ Wu Anna H AH Pike Malcolm C MC Ness Roberta B RB Moysich Kirsten K Chenevix-Trench Georgia G Beesley Jonathan J Webb Penelope M PM Chang-Claude Jenny J Wang-Gohrke Shan S Goodman Marc T MT Lurie Galina G Thompson Pamela J PJ Carney Michael E ME Hogdall Estrid E Kjaer Susanne Kruger SK Hogdall Claus C Goode Ellen L EL Cunningham Julie M JM Fridley Brooke L BL Vierkant Robert A RA Berchuck Andrew A Moorman Patricia G PG Schildkraut Joellen M JM Palmieri Rachel T RT Cramer Daniel W DW Terry Kathryn L KL Yang Hannah P HP Garcia-Closas Montserrat M Chanock Stephen S Lissowska Jolanta J Song Honglin H Pharoah Paul D P PD Shah Mitul M Perkins Barbara B McGuire Valerie V Whittemore Alice S AS Di Cioccio Richard A RA Gentry-Maharaj Aleksandra A Menon Usha U Gayther Simon A SA Ramus Susan J SJ Ziogas Argyrios A Brewster Wendy W Anton-Culver Hoda H Pearce Celeste Leigh CL
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20100101 1
We genotyped 13 single nucleotide polymorphisms (SNPs) in the estrogen receptor alpha gene (ESR1) region in three population-based case-control studies of epithelial ovarian cancer conducted in the United States, comprising a total of 1,128 and 1,866 non-Hispanic white invasive cases and controls, respectively. A SNP 19 kb downstream of ESR1 (rs2295190, G-to-T change) was associated with invasive ovarian cancer risk, with a per-T-allele odds ratio (OR) of 1.24 [95% confidence interval (CI), 1.06 ...[more]