Ontology highlight
ABSTRACT:
SUBMITTER: Rolfe A
PROVIDER: S-EPMC2864497 | biostudies-literature | 2010 Mar
REPOSITORIES: biostudies-literature
Rolfe Alan A Samarakoon Thiwanka B TB Hanson Paul R PR
Organic letters 20100301 6
A formal [4+3] epoxide cascade protocol utilizing ambiphilic sulfonamides and a variety of epoxides (masked ambiphiles) has been developed for the generation of benzothiaoxazepine-1,1'-dioxides and oxathiazepine-1,1'-dioxides. This protocol combines an epoxide ring-opening with either an S(N)Ar or oxa-Michael cyclization pathway. ...[more]