Ontology highlight
ABSTRACT:
SUBMITTER: Eberlin LS
PROVIDER: S-EPMC2872194 | biostudies-literature | 2010 May
REPOSITORIES: biostudies-literature
Eberlin Livia S LS Dill Allison L AL Costa Anthony B AB Ifa Demian R DR Cheng Liang L Masterson Timothy T Koch Michael M Ratliff Timothy L TL Cooks R Graham RG
Analytical chemistry 20100501 9
Development of methods for rapid distinction between cancerous and non-neoplastic tissues is an important goal in disease diagnosis. To this end, desorption electrospray ionization mass spectrometry (DESI-MS) imaging was applied to analyze the lipid profiles of thin tissue sections of 68 samples of human prostate cancer and normal tissue. The disease state of the tissue sections was determined by independent histopathological examination. Cholesterol sulfate was identified as a differentiating c ...[more]