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Pd-catalyzed cross-coupling reactions of amides and aryl mesylates.

ABSTRACT: A catalyst, based on a biarylphosphine ligand, for the Pd-catalyzed cross-coupling reactions of amides and aryl mesylates is described. This system allows an array of aryl and heteroaryl mesylates to be transformed into the corresponding N-aryl amides in moderate to excellent yields.

SUBMITTER: Dooleweerdt K 

PROVIDER: S-EPMC2874946 | biostudies-literature | 2010 May

REPOSITORIES: biostudies-literature

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Pd-catalyzed cross-coupling reactions of amides and aryl mesylates.

Dooleweerdt Karin K   Fors Brett P BP   Buchwald Stephen L SL  

Organic letters 20100501 10

A catalyst, based on a biarylphosphine ligand, for the Pd-catalyzed cross-coupling reactions of amides and aryl mesylates is described. This system allows an array of aryl and heteroaryl mesylates to be transformed into the corresponding N-aryl amides in moderate to excellent yields. ...[more]

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