Ontology highlight
ABSTRACT:
SUBMITTER: Schutzer SE
PROVIDER: S-EPMC2881861 | biostudies-literature | 2010 Jun
REPOSITORIES: biostudies-literature
Schutzer Steven E SE Liu Tao T Natelson Benjamin H BH Angel Thomas E TE Schepmoes Athena A AA Purvine Samuel O SO Hixson Kim K KK Lipton Mary S MS Camp David G DG Coyle Patricia K PK Smith Richard D RD Bergquist Jonas J
PloS one 20100611 6
<h4>Background</h4>Knowledge of the entire protein content, the proteome, of normal human cerebrospinal fluid (CSF) would enable insights into neurologic and psychiatric disorders. Until now technologic hurdles and access to true normal samples hindered attaining this goal.<h4>Methods and principal findings</h4>We applied immunoaffinity separation and high sensitivity and resolution liquid chromatography-mass spectrometry to examine CSF from healthy normal individuals. 2630 proteins in CSF from ...[more]