Ontology highlight
ABSTRACT:
SUBMITTER: Heitz BA
PROVIDER: S-EPMC2882248 | biostudies-literature | 2010 May
REPOSITORIES: biostudies-literature
Heitz Benjamin A BA Jones Ian W IW Hall Henry K HK Aspinwall Craig A CA Saavedra S Scott SS
Journal of the American Chemical Society 20100501 20
Suspended planar lipid membranes (or black lipid membranes (BLMs)) are widely used for studying reconstituted ion channels, although they lack the chemical and mechanical stability needed for incorporation into high-throughput biosensors and biochips. Lipid polymerization enhances BLM stability but is incompatible with ion channel function when membrane fluidity is required. Here, we demonstrate the preparation of a highly stable BLM that retains significant fluidity by using a mixture of polyme ...[more]