Ontology highlight
ABSTRACT:
SUBMITTER: Mueller NH
PROVIDER: S-EPMC2888152 | biostudies-literature | 2010 May
REPOSITORIES: biostudies-literature
The Journal of general virology 20100120 Pt 5
Efficient replication of varicella-zoster virus (VZV) in cell culture requires expression of protein encoded by VZV open reading frame 63 (ORF63p). Two-dimensional gel analysis demonstrates that ORF63p is extensively modified. Mass spectroscopy analysis of ORF63p isolated from transiently transfected HEK 293 and stably transfected MeWo cells identified 10 phosphorylated residues. In VZV-infected MeWo cells, only six phosphorylated residues were detected. This report identifies phosphorylation of ...[more]