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Efficient methodology for the synthesis of 3-amino-1,2,4-triazoles.


ABSTRACT: A general and efficient method for the preparation of 3-amino-1,2,4-triazoles has been developed. The desired 3-amino-1,2,4-triazoles (1) were prepared in good overall yield via two convergent routes. The key intermediate within both routes is substituted hydrazinecarboximidamide derivative 2.

SUBMITTER: Noel R 

PROVIDER: S-EPMC2890234 | biostudies-literature | 2009 Oct

REPOSITORIES: biostudies-literature

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Efficient methodology for the synthesis of 3-amino-1,2,4-triazoles.

Noël Romain R   Song Xinyi X   Jiang Rong R   Chalmers Michael J MJ   Griffin Patrick R PR   Kamenecka Theodore M TM  

The Journal of organic chemistry 20091001 19


A general and efficient method for the preparation of 3-amino-1,2,4-triazoles has been developed. The desired 3-amino-1,2,4-triazoles (1) were prepared in good overall yield via two convergent routes. The key intermediate within both routes is substituted hydrazinecarboximidamide derivative 2. ...[more]

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