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Kinesin-14: the roots of reversal.


ABSTRACT: Kinesin-14 motor proteins step towards microtubule minus ends, in the opposite direction to other kinesins. Work on the still-enigmatic kinesin-14 mechanism published in BMC Structural Biology shows that the carboxyl terminus of the motor head undergoes a dock-undock cycle, like that of plus-end-directed kinesins.

SUBMITTER: Cross RA 

PROVIDER: S-EPMC2922096 | biostudies-literature | 2010 Aug

REPOSITORIES: biostudies-literature

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Kinesin-14: the roots of reversal.

Cross Robert A RA  

BMC biology 20100816


Kinesin-14 motor proteins step towards microtubule minus ends, in the opposite direction to other kinesins. Work on the still-enigmatic kinesin-14 mechanism published in BMC Structural Biology shows that the carboxyl terminus of the motor head undergoes a dock-undock cycle, like that of plus-end-directed kinesins. ...[more]

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