Ontology highlight
ABSTRACT:
SUBMITTER: Kim MB
PROVIDER: S-EPMC2927847 | biostudies-literature | 2010 Aug
REPOSITORIES: biostudies-literature
Kim Michelle B MB Shaw Jared T JT
Organic letters 20100801 15
An efficient, convergent synthesis of totarol by a diastereoselective epoxide/alkene/arene bicyclization is described. The reported synthesis enables the preparation of related diterpenes totaradiol and totarolone as well as previously unavailable derivatives that exhibit comparable inhibition of the bacterial cell division protein FtsZ. ...[more]