Ontology highlight
ABSTRACT:
SUBMITTER: Bizzarri C
PROVIDER: S-EPMC2928344 | biostudies-literature | 2010 Sep
REPOSITORIES: biostudies-literature
Bizzarri Carla C Pitocco Dario D Napoli Nicola N Di Stasio Enrico E Maggi Daria D Manfrini Silvia S Suraci Concetta C Cavallo Maria Gisella MG Cappa Marco M Ghirlanda Giovanni G Pozzilli Paolo P
Diabetes care 20100901 9
<h4>Objective</h4>We investigated whether supplementation of the active form of vitamin D (calcitriol) in recent-onset type 1 diabetes can protect beta-cell function evaluated by C-peptide and improve glycemic control assessed by A1C and insulin requirement.<h4>Research design and methods</h4>Thirty-four subjects (aged 11-35 years, median 18 years) with recent-onset type 1 diabetes and high basal C-peptide >0.25 nmol/l were randomized in a double-blind trial to 0.25 microg/day calcitriol or plac ...[more]