Ontology highlight
ABSTRACT:
SUBMITTER: Huang CR
PROVIDER: S-EPMC2943426 | biostudies-literature | 2010 Jun
REPOSITORIES: biostudies-literature
Cell 20100601 7
Characterizing structural variants in the human genome is of great importance, but a genome wide analysis to detect interspersed repeats has not been done. Thus, the degree to which mobile DNAs contribute to genetic diversity, heritable disease, and oncogenesis remains speculative. We perform transposon insertion profiling by microarray (TIP-chip) to map human L1(Ta) retrotransposons (LINE-1 s) genome-wide. This identified numerous novel human L1(Ta) insertional polymorphisms with highly variant ...[more]