Dataset Information
The CoFactor database: organic cofactors in enzyme catalysis.
Ontology highlight
ABSTRACT: Motivation
Organic enzyme cofactors are involved in many enzyme reactions. Therefore, the analysis of cofactors is crucial to gain a better understanding of enzyme catalysis. To aid this, we have created the CoFactor database.Results
CoFactor provides a web interface to access hand-curated data extracted from the literature on organic enzyme cofactors in biocatalysis, as well as automatically collected information. CoFactor includes information on the conformational and solvent accessibility variation of the enzyme-bound cofactors, as well as mechanistic and structural information about the hosting enzymes.Availability
The database is publicly available and can be accessed at http://www.ebi.ac.uk/thornton-srv/databases/CoFactor.
SUBMITTER: Fischer JD
PROVIDER: S-EPMC2944199 | biostudies-literature | 2010 Oct
REPOSITORIES: biostudies-literature
Publications
The CoFactor database: organic cofactors in enzyme catalysis.
Bioinformatics (Oxford, England) 20100802 19
<h4>Motivation</h4>Organic enzyme cofactors are involved in many enzyme reactions. Therefore, the analysis of cofactors is crucial to gain a better understanding of enzyme catalysis. To aid this, we have created the CoFactor database.<h4>Results</h4>CoFactor provides a web interface to access hand-curated data extracted from the literature on organic enzyme cofactors in biocatalysis, as well as automatically collected information. CoFactor includes information on the conformational and solvent a ...[more]