Ontology highlight
ABSTRACT:
SUBMITTER: Ling J
PROVIDER: S-EPMC2944653 | biostudies-literature | 2009 Mar
REPOSITORIES: biostudies-literature
Ling Jiqiang J So Byung Ran BR Yadavalli Srujana S SS Roy Hervé H Shoji Shinichiro S Fredrick Kurt K Musier-Forsyth Karin K Ibba Michael M
Molecular cell 20090301 5
Faithful translation of the genetic code depends on the GTPase EF-Tu delivering correctly charged aminoacyl-tRNAs to the ribosome for pairing with cognate codons. The accurate coupling of cognate amino acids and tRNAs by the aminoacyl-tRNA synthetases is achieved through a combination of substrate specificity and product editing. Once released by aminoacyl-tRNA synthetases, both cognate and near-cognate aminoacyl-tRNAs were considered to be committed to ribosomal protein synthesis through their ...[more]