Ontology highlight
ABSTRACT:
SUBMITTER: Gatto NM
PROVIDER: S-EPMC2945263 | biostudies-literature | 2010
REPOSITORIES: biostudies-literature
Gatto Nicole M NM Rhodes Shannon L SL Manthripragada Angelika D AD Bronstein Jeff J Cockburn Myles M Farrer Matt M Ritz Beate B
Neuroepidemiology 20100724 3
<h4>Background</h4>Although of great interest and suggested in prior reports, possible α-synuclein (SNCA) gene-environment interactions have not been well investigated in humans.<h4>Methods</h4>We used a population-based approach to examine whether the risk of Parkinson's disease (PD) depended on the combined presence of SNCA variations and two important environmental factors, pesticide exposures and smoking.<h4>Results/conclusions</h4>Similar to recent meta- and pooled analyses, our data sugges ...[more]