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Ethyl 4-hydroxy-methyl-2-methyl-pyridine-5-carboxyl-ate.

ABSTRACT: The title compound, C(10)H(13)NO(3), was obtained as a by-product of the aldolization reaction of furo[3,4-c]pyridin-3(1H)-one with thio-phene-2-carboxaldehyde. The substituents on the pyridine ring are nearly coplanar, with an 8.1?(2)° rotation of the hydroxmethyl group from this plane. The mol-ecules assemble in the crystal structure as chains via O-H?N hydrogen bonding between the pyridine N atom and a neighbouring hydroxy-methyl OH group.

SUBMITTER: Boyd PD

PROVIDER: S-EPMC2961239 | biostudies-literature | 2008 Apr

REPOSITORIES: biostudies-literature

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Ethyl 4-hydroxy-methyl-2-methyl-pyridine-5-carboxyl-ate.

Boyd Peter D W PD Lena Gersande G Spicer Julie A JA

Acta crystallographica. Section E, Structure reports online 20080423 Pt 5

The title compound, C(10)H(13)NO(3), was obtained as a by-product of the aldolization reaction of furo[3,4-c]pyridin-3(1H)-one with thio-phene-2-carboxaldehyde. The substituents on the pyridine ring are nearly coplanar, with an 8.1 (2)° rotation of the hydroxmethyl group from this plane. The mol-ecules assemble in the crystal structure as chains via O-H⋯N hydrogen bonding between the pyridine N atom and a neighbouring hydroxy-methyl OH group. ...[more]

PMID: 21202367

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