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4-Anilino-1-benzyl-piperidine-4-carbo-nitrile.

ABSTRACT: The title mol-ecule, C(19)H(21)N(3), an important precursor in the synthesis of porphyrin-fentanyl conjugates, has its piperidine ring in the chair conformation, with endocyclic torsion-angle magnitudes in the range 53.26?(8)-60.63?(9)°. The C N group is axial, while the CH(2)Ph and NHPh groups are equatorial. The NH group does not engage in strong hydrogen bonding, but forms an inter-molecular N-H?N inter-action.

SUBMITTER: Allam KK

PROVIDER: S-EPMC2961292 | biostudies-literature | 2008 Apr

REPOSITORIES: biostudies-literature

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4-Anilino-1-benzyl-piperidine-4-carbo-nitrile.

Allam Kiran K KK Fronczek Frank R FR Vicente M Graça H MG

Acta crystallographica. Section E, Structure reports online 20080416 Pt 5

The title mol-ecule, C(19)H(21)N(3), an important precursor in the synthesis of porphyrin-fentanyl conjugates, has its piperidine ring in the chair conformation, with endocyclic torsion-angle magnitudes in the range 53.26 (8)-60.63 (9)°. The C N group is axial, while the CH(2)Ph and NHPh groups are equatorial. The NH group does not engage in strong hydrogen bonding, but forms an inter-molecular N-H⋯N inter-action. ...[more]

PMID: 21202327

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