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T-3-Benzyl-r-2,c-6-bis-(4-methoxy-phen-yl)-piperidin-4-one.

ABSTRACT: In the title compound, C(26)H(27)NO(3), the piperidine ring adopts a chair conformation. The two methoxy-phenyl groups attached to the piperidine ring at positions 2 and 6 have equatorial orientations and make a dihedral angle of 87.33?(8)°. The benzyl group at position 3 has an equatorial orientation. The phenyl ring of the benzyl group makes dihedral angles of 75.60?(9) and 73.69?(9)° with the two benzene rings. Mol-ecules are linked by inter-molecular N-H?O and C-H?O hydrogen bonds and by C-H?? inter-actions.

SUBMITTER: Jayabharathi J

PROVIDER: S-EPMC2961717 | biostudies-literature | 2008 Jun

REPOSITORIES: biostudies-literature

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t-3-Benzyl-r-2,c-6-bis-(4-methoxy-phen-yl)-piperidin-4-one.

Jayabharathi J J Thangamani A A Balamurugan S S Thiruvalluvar A A Linden A A

Acta crystallographica. Section E, Structure reports online 20080607 Pt 7

In the title compound, C(26)H(27)NO(3), the piperidine ring adopts a chair conformation. The two methoxy-phenyl groups attached to the piperidine ring at positions 2 and 6 have equatorial orientations and make a dihedral angle of 87.33 (8)°. The benzyl group at position 3 has an equatorial orientation. The phenyl ring of the benzyl group makes dihedral angles of 75.60 (9) and 73.69 (9)° with the two benzene rings. Mol-ecules are linked by inter-molecular N-H⋯O and C-H⋯O hydrogen bonds and by C-H ...[more]

PMID: 21202824

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t-3-Benzyl-r-2,c-6-bis-(4-methoxy-phen-yl)piperidin-4-one oxime.

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Project description:In the title compound, C(23)H(27)NO(4), the piperidine ring adopts a distorted boat conformation. The meth-oxy groups lie in the plane of benzene rings to which they are attached [maximum deviations of 0.014?(3) and 0.007?(3)?Å]. The benzene rings are oriented at angles of 67.2?(1) and 87.0?(1)° with respect to the best plane through the four co-planar atoms of the piperidine ring.

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