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3-(4-Fluoro-phen-yl)-2-(4-pyrid-yl)pyrido[2,3-b]pyrazine.

ABSTRACT: In the crystal structure of the title compound, C(18)H(11)FN(4), the pyridopyrazine ring makes dihedral angles of 34.67?(7) and 52.24?(7)° with the 4-fluoro-phenyl and pyridine rings, respectively. The 4-fluoro-phenyl ring makes a dihedral angle of 59.56?(9)° with the pyridine ring.

SUBMITTER: Koch P

PROVIDER: S-EPMC2970414 | biostudies-literature | 2009 Sep

REPOSITORIES: biostudies-literature

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3-(4-Fluoro-phen-yl)-2-(4-pyrid-yl)pyrido[2,3-b]pyrazine.

Koch Pierre P Schollmeyer Dieter D Laufer Stefan S

Acta crystallographica. Section E, Structure reports online 20090926 Pt 10

In the crystal structure of the title compound, C(18)H(11)FN(4), the pyridopyrazine ring makes dihedral angles of 34.67 (7) and 52.24 (7)° with the 4-fluoro-phenyl and pyridine rings, respectively. The 4-fluoro-phenyl ring makes a dihedral angle of 59.56 (9)° with the pyridine ring. ...[more]

PMID: 21577988

Similar Datasets

2-(4-Fluoro-phen-yl)-3-(4-pyrid-yl)pyrido[2,3-b]pyrazine.

Project description:In the crystal structure of the title compound, C(18)H(11)FN(4), the pyridopyrazine system makes dihedral angles of 45.51?(7) and 44.75?(7)° with the attached 4-fluoro-phenyl ring and the pyridine ring, respectively. The 4-fluoro-phenyl ring makes a dihedral angle of 54.54?(8)° with the pyridine ring. The pyridine ring part of the pyridopyrazine ring and the pyrazine ring of two c-glide-plane-related mol-ecules form ?-? inter-actions. The angle between the planes is 2.09?(7)° and the distance between the centroids is 3.557?(1)Å.

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Project description:In the title compound, C(20)H(17)F(2)NO(4)S(2), the dihedral angles between the o-xylene ring and the fluoro-benzene rings are 31.7?(1) and 32.8?(1)°, and the dihedral angle between the fluoro-benzene rings is 50.9?(1)°. The C-N-S-C torsion angles are 76.7?(2) and 101.8?(2)°. In the crystal, mol-ecules are connected by C-H?O inter-actions into sheets in the ab plane.

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Project description:Crystals of the title compound, C(23)H(17)B(3)F(3)NO(3), were obtained unintentionally by slow evaporation of a chloro-form solution of the preformed boroxine-pyridine adduct. The mol-ecule contains three fluoro-substituted benzene rings, each bonded to one of the three B atoms of a six-membered boroxine ring. A pyridyl ring is also bound to one of the B atoms through a Lewis acid-base inter-action. The binding of the pyridyl substituent causes the otherwise planar boroxine ring to twist, resulting in a maximum torsion angle within the ring of 17.6?(2)°.

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5-(2,3-Dichloro-phen-yl)-2-fluoro-pyridine.

Project description:In the title compound, C(11)H(6)Cl(2)FN, the dichloro-benzene and the 2-fluoro-pyridine rings are oriented at a dihedral angle of 47.73 (3)°. In the crystal, pairs of C-H⋯N inter-actions link the mol-ecules into dimers with R(2) (2)(12) motifs. Mol-ecules are arranged in stacks extending along [100] via π-π inter-actions with a centroid-centroid distance of 3.8889 (3) Å.

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Methyl pyrido[2,3-b]pyrazine-3-carboxyl-ate.

Project description:The asymmetric unit of the title compound, C(9)H(7)N(3)O(2), is composed of two independent mol-ecules. The crystal structure is stabilized by C-H?O and C-H?N hydrogen bonds, forming a three-dimensional network. The crystal structure also features pyrazine-pyrazine ?-? inter-actions [centroid-centroid distance = 3.6994?(5)?Å] and also pyridine-pyrazine ?-? inter-actions [centroid-centroid distance = 3.6374?(5)?Å].

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(11-Methyl-pyrido[2,3-b][1,4]benzo-diazepin-6-yl)(phen-yl)methanone.

Project description:In the title compound, C(20)H(15)N(3)O, the diazepine ring adopts a boat conformation. The dihedral angle between pyridine and benzene rings is 55.2 (1)°. The benzoyl phenyl ring forms dihedral angles of 49.4 (1) and 75.9 (1)°, respectively, with the pyridine and benzene rings. In the crystal, mol-ecules are linked into centrosymmetric dimers by pairs of C-H⋯N hydrogen bonds.

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