Ontology highlight
ABSTRACT:
SUBMITTER: Mirensky TL
PROVIDER: S-EPMC2971535 | biostudies-literature | 2010 Jun
REPOSITORIES: biostudies-literature
Mirensky Tamar L TL Hibino Narutoshi N Sawh-Martinez Rajendra F RF Yi Tai T Villalona Gustavo G Shinoka Toshiharu T Breuer Christopher K CK
Journal of pediatric surgery 20100601 6
<h4>Purpose</h4>Use of tissue-engineered vascular grafts (TEVGs) in the repair of congenital heart defects provides growth and remodeling potential. Little is known about the mechanisms involved in neovessel formation. We sought to define the role of seeded monocytes derived from bone marrow mononuclear cells (BM-MNCs) on neovessel formation.<h4>Methods</h4>Small diameter biodegradable tubular scaffolds were constructed. Scaffolds were seeded with the entire population of BM-MNC (n = 15), BM-MNC ...[more]